Jeffrey Donovan stars as Detective David Creegan, who after surviving a near fatal gunshot wound to the head, takes a 12-month psychological leave of absence. He returns to work for the FBI's new Organized and Serial Crime Unit, a rapid-response, elite crime squad. His brush with death renders him fearless in his relentless pursuit of justice as he and his partner Susan Branca (Vera Farminga) specialize in solving shocking, high profile crimes.