Blade: The Series follows the adventures of the half-human, half-vampire vampire-hunter, Blade (, ), as he fights to prevent the takeover of vampires over mankind. At his side is Krista Starr (, ), an ex-military veteran who seeks vengeance against all vampires due to the death of her brother, and his gadget-man, Shen (, ), who aid him in his quest. Blade's main adversary in this series is Marcus Van Sciver (, ), who is the leader of the house of Chthon.